As the plague decimates Eyam, Anna is gnawed by doubts about God. She can't understand how an infinitely loving deity would inflict so much suffering on the world.

This imagery is a bit much, but though it's gross, it shows us the immense physical suffering associated with the plague. It also gives us an idea of the emotional suffering that one endures watching a loved one go through something so horrific.

With the plague rapidly taking hold, the villagers go legit insane and lynch Anys Gowdie because they think that she's a witch. They're desperate to pin the blame for their situation on some outside force; it's the only way they can make sense of their suffering.