Deadpool / Wade Wilson (Ryan Reynolds)’s Timeline and Summary

Wade meets Vanessa at Sister Margaret's, and, by the end of the year, they're engaged.
Wade is diagnosed with terminal cancer and walks out on Vanessa in the middle of the night.
After initially resisting, Wade consents to treatment at the Weapon X workshop. His mutant DNA is unleashed, his cancer is effectively cured, and he's terribly disfigured.
Wade adopts the masked persona "Deadpool."
Deadpool kills several low-level thugs on his way to Ajax. He plans to make Ajax fix his face; then he's going to kill him.
Deadpool intercepts Ajax's convoy. Colossus and Negasonic Teenage Warhead intervene; they want Deadpool to go straight and join the X-Men.
In the chaos, Ajax escapes from Deadpool, and Deadpool escapes from Colossus.
Ajax kidnaps Vanessa and takes her to an abandoned shipyard.
After enlisting the help of Colossus and Negasonic Teenage Warhead, Deadpool battles Ajax and his thugs at the shipyard.
Ajax reveals that he can't fix Deadpool's face—never could—and Deadpool kills him.
Deadpool and Vanessa are reunited. She's angry at first, but they quickly make up (and out).