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Molecular Genetics: DNA 466 Views
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In this video from our course on molecular genetics, learn all about animal cloning.
Transcript
- 00:14
We are here with Dr. Ruth Tennen to talk about molecular genetics, here at Shmoop Global Headquarters in Mountain View, California.
- 00:23
Dr. Ruth here is a PhD, trying to cure cancer.
- 00:26
So if you ever want to make your parents really proud of you, follow in her footsteps.
- 00:31
I can't think of much better on earth to do with your life...
- 00:36
Let's just jump right in to Lesson 1 here.
Full Transcript
- 00:38
We're gonna cover genetic code and DNA/RNA structure.
- 00:43
So, Dr. Ruth, what does DNA stand for? Like...I can't even spell it...
- 00:52
So DNA stands for deoxyribonucleic acid.
- 00:54
So all the letters are in there somewhere.
- 00:55
Nucleic acid is basically any polymer or any group of molecules in your cells that are composed of nucleotides.
- 01:03
So it has three parts. It has a base made of nitrogen...
- 01:05
...it has a phosphate group... and it has a sugar.
- 01:07
Okay, so we gotta back you up.
- 01:09
Polymer...that's many mer...
- 01:12
Yes, many mer. That's exactly it.
- 01:14
You have one unit of molecule, and then you string a bunch of them together. So it's a monomer to a polymer...exactly, just like beads.
- 01:22
There are a couple other five-dollar words. What is a phosphate group?
- 01:26
I'm picturing... you go to that old-style Coca-Cola stand with a hot dog and a shake...
- 01:32
So a phosphate group basically has a phosphorus and some oxygen atoms in it.
- 01:36
And it forms the backbone of the DNA, so basically it's all along the outside of the DNA molecule...
- 01:41
...and they link up together to form the chain.
- 01:44
And a nitrogen base...like...nitrogen's a molecule?
- 01:50
Nitrogen's another atom.
- 01:51
And what is its base? The ATCG is adenine, thytozine, cytosine, guanine... if I remember from high school a million years ago...
- 02:01
If you can, break down the word for us. What is "deoxy"?
- 02:05
...No longer oxy?
- 02:06
That's exactly it. It means it's missing an oxygen.
- 02:09
So basically, in the sugar molecule that's part of the nucleotide...
- 02:12
...in RNA, there's an extra oxygen compared to DNA.
- 02:15
So deoxy basically means missing an oxygen.
- 02:18
Got it. And "ribo"... that's something to do with Eve and Adam...?
- 02:24
So ribose is just a type of sugar.
- 02:26
And then nucleic...?
- 02:30
Yeah, so it's the same idea. The nucleus is made up of these nucleotides.
- 02:37
So deoxyribo tells us that it's DNA, not RNA, 'cause the sugar is missing an oxygen molecule.
- 02:47
Okay, so that's what DNA stands for. That's what comprises DNA. But what is DNA? Like, what does it do for us? How does it function...other than to confuse high school children?
- 02:59
It's actually super important. It's basically the biological blueprint that makes us who we are.
- 03:02
So it contains all our genetic information. We get half of our DNA from our mom, half from our dad.
- 03:07
And then every time our cells divide, the DNA gets split into the two cells.
- 03:11
So it kind of keeps going through all the different cells.
- 03:15
And what is its primary function? Like, walk us through the creation of the code of proteins and how that kind of builds a human being.
- 03:26
So in basic terms, you start with the DNA. You get 23 chromosomes from your mom, 23 from your dad. So that's 46 total.
- 03:33
The DNA codes for an intermediate called RNA, through a process called transcription.
- 03:39
And the RNA gets turned into proteins, ultimately, and proteins are kind of the workhorses in your cells.
- 03:43
They do all the work, they form the structures in your body, they do all the enzyme processes.
- 03:47
So they give you all your traits, they can have things to do with your personality, your appearance, all sorts of things.
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