The Crying of Lot 49 Drugs and Alcohol Quotes

How we cite our quotes: (Chapter.Paragraph)

Quote #10

The day she'd left him for San Narciso was the day she'd seen Mucho for the last time. (5.323)

Here, as elsewhere in the book, drugs are seen to sever human relationships. Do you think the book has a positive or a negative view of drug use? Is it possible to tell?